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4-Hydroxycinnamic acid

  • ProductNo:470898-1a78fec1-cec2-4850-83ea-08efb101d69d
    Packing:
  • CasNo.:7400-08-0
    MW:164.161
  • Purity:>
    Content:
  • MF:C9H8O3
    Apply:

Export Top Purity 4-Hydroxycinnamic acid 7400-08-0 In Stock

  • Molecular Formula:C9H8O3
  • Molecular Weight:164.161
  • Appearance/Colour:Light yellow to beige crystalline powder 
  • Vapor Pressure:7.19E-05mmHg at 25°C 
  • Melting Point:212-214 °C 
  • Refractive Index:1.6 
  • Boiling Point:346.052 °C at 760 mmHg 
  • PKA:4.65±0.10(Predicted) 
  • Flash Point:177.284 °C 
  • PSA:57.53000 
  • Density:1.33 g/cm3 
  • LogP:1.49000 

p-Hydroxy-cinnamic acid(Cas 7400-08-0) Usage

Hazard

Moderately toxic.

Safety Profile

Moderarely toxic by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes. See also COUMARIN

Application

p-Hydroxycinnamic acid is mainly used as an intermediate in the pharmaceutical and perfume industries. It can react with dimethyl sulfate to produce p-anisaldehyde, react with acetaldehyde to produce p-hydroxycinnamaldehyde, and further oxidize it to produce cinnamic acid. This product can be directly oxidized to produce 4-Hydroxybenzoic acid and reduction to produce 4-Hydroxybenzyl alcohol.

Definition

ChEBI: 4-coumaric acid is a coumaric acid in which the hydroxy substituent is located at C-4 of the phenyl ring. It has a role as a plant metabolite. It is a conjugate acid of a 4-coumarate.

InChI:InChI=1/C9H8O3/c1-6(9(11)12)7-2-4-8(10)5-3-7/h2-5,10H,1H2,(H,11,12)

7400-08-0 Relevant articles

Photoinduced Regioselective Olefination of Arenes at Proximal and Distal Sites

Ali, Wajid,Anjana, S. S.,Bhattacharya, Trisha,Chandrashekar, Hediyala B.,Goswami, Nupur,Guin, Srimanta,Maiti, Debabrata,Panda, Sanjib,Prakash, Gaurav,Saha, Argha,Sasmal, Sheuli,Sinha, Soumya Kumar

, p. 1929 - 1940 (2022/02/01)

The Fujiwara-Moritani reaction has had a...

Design, synthesis, and evaluation of different scaffold derivatives against NS2B-NS3 protease of dengue virus

Ganji, Lata R.,Gandhi, Lekha,Musturi, Venkataramana,Kanyalkar, Meena A.

, p. 285 - 301 (2020/11/19)

The number of deaths or critical health ...

Dual Nickel/Ruthenium Strategy for Photoinduced Decarboxylative Cross-Coupling of α,β-Unsaturated Carboxylic Acids with Cycloketone Oxime Esters

Gao, Ang,Jiang, Run-Chuang,Liu, Chuang-Chuang,Liu, Qi-Le,Lu, Xiao-Yu,Xia, Ze-Jie

supporting information, p. 8829 - 8842 (2021/06/30)

Herein, a dual nickel/ruthenium strategy...

Ballodiolic acid a and b: Two new ros, (? oh), (onoo? ) scavenging and potent antimicrobial constituents isolated from ballota pseudodictamnus (l.) benth.

Ahmad, Ijaz,Ahmad, Nisar,Alobaid, Abdulrahman,Amin, Syed Badar,Bari, Ahmed,Fozia,Mahmood, Hafiz Majid,Shaheen, Asmat,Sohaib, Muhammad,Ullah, Riaz

, (2021/04/07)

Bioassays guided phytochemical investiga...

7400-08-0 Process route

cyanidin 3-O-[2-O-(β-xylopyranosyl)-6-O-(4-O-(6-O-(trans-feruloyl)-β-glucopyranosyl)-trans-p-coumaroyl)-β-glucopyranoside]-5-O-[6-O-(malonyl)-β-glucopyranoside]

cyanidin 3-O-[2-O-(β-xylopyranosyl)-6-O-(4-O-(6-O-(trans-feruloyl)-β-glucopyranosyl)-trans-p-coumaroyl)-β-glucopyranoside]-5-O-[6-O-(malonyl)-β-glucopyranoside]

3-(4-hydroxy-3-methoxyphenyl)acrylic acid
1135-24-6,537-98-4

3-(4-hydroxy-3-methoxyphenyl)acrylic acid

D-xylose
58-86-6

D-xylose

cyanidin
13306-05-3

cyanidin

D-glucose
50-99-7

D-glucose

malonic acid
141-82-2

malonic acid

para-coumaric acid
7400-08-0,50940-26-6

para-coumaric acid

Conditions
Conditions Yield
With hydrogenchloride; water; at 100 ℃; for 2h;
cyanidin 3-O-[2-O-(2-O-(trans-feruloyl)-β-xylopyranosyl)-6-O-(4-O-(β-glucopyranosyl)-trans-pcoumaroyl)-β-glucopyranoside]-5-O-[6-O-(malonyl)-β-glucopyranoside]

cyanidin 3-O-[2-O-(2-O-(trans-feruloyl)-β-xylopyranosyl)-6-O-(4-O-(β-glucopyranosyl)-trans-pcoumaroyl)-β-glucopyranoside]-5-O-[6-O-(malonyl)-β-glucopyranoside]

3-(4-hydroxy-3-methoxyphenyl)acrylic acid
1135-24-6,537-98-4

3-(4-hydroxy-3-methoxyphenyl)acrylic acid

D-xylose
58-86-6

D-xylose

cyanidin
13306-05-3

cyanidin

D-glucose
50-99-7

D-glucose

malonic acid
141-82-2

malonic acid

para-coumaric acid
7400-08-0,50940-26-6

para-coumaric acid

Conditions
Conditions Yield
With hydrogenchloride; water; at 100 ℃; for 2h;

7400-08-0 Upstream products

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    acetic anhydride

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    4-hydroxy-benzaldehyde

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    malonic acid

  • 540-38-5
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    p-Iodophenol

7400-08-0 Downstream products

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    4-(3-oxy-[1,2,3]oxadiazol-5-yl)-phenol

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    hydroxy-(4-hydroxy-phenyl)-acetaldehyde

  • 3943-97-3
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    methyl p-hydroxycinnamate

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    4-trimethylsiloxycinnamic acid